Plasma medicine has, in a remarkably short period of time, led to revelations across the entire clinical continuum from risk assessment in healthy individuals to the treatment of complex diseases. With the enormous treasure-trove of data about the human genome produced by the research, spawning a whole new era of digital technologies and systems, researchers and clinicians now have more robust tools to study the role that non-invasive factors have in complex diseases. Plasma medicine is a growing field combining plasma physics, biology, and clinical medicine and has an impact in several important areas in therapeutic patient care, combining plasma physics, biology, and clinical medicine. Earlier, plasmas in medicine were used in non-contact hemostasis and electrosurgery for cautery, while presently, non-thermal plasmas have attained widespread use in medicine due to their effectiveness and compatibility with biological systems. The most active areas of plasma technology applicati...